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| Alkaline Phosphatase, Color Endpoint (140) | |
| Product | Alkaline Phosphatase, Color Endpoint (140) |
|---|---|
| Catalog Number | BQ 003A-CR |
| Quantity | 140 Tests |
| Sample Type | Serum |
| Description | For the direct colorimetric determination of alkaline phosphatase in human serum. Distributed in almost every tissue of the body, serum alkaline phosphatase (ALP) levels are of interest in the diagnosis of hepatobiliary disorder and bone disease. Most of the ALP in normal adults serum is from the liver or biliary tract. Normal alkaline phosphatase levels are age dependent, and levels are elevated during periods of active bone growth. Moderate elevations of ALP (not involving the liver or bone) may be attributed to Hodgins' disease, congestive heart failure, and abdominal bacterial infections. Elevations also occur in the third trimester of pregnancy. Earlier methods were based on the measurement of phosphate liberated by the action of the enzyme on a beta-glycerolphosphate substrate or on the measurement of phenol liberated from disodium phenyl phosphate substrate. Many of these substrates are unstable in solution and need to be prepared fresh daily. The substrate developed by Roy, which uses sodium thymolphthalein monophosphate is stable for one year when properly stored. |
| Species | Human |
